Research Publications

To confront the COVID-19 pandemic, MassCPR has brought together scientists to work in new ways that are more collaborative, open and dedicated to the continual pursuit of transformative knowledge for the benefit of humanity. Below, please find a curated list of the peer-reviewed research publications resulting from those collaborations.

General

Li JZ, Yu XG. Overcoming Challenges in COVID-19 Translational Research. J Infect Dis. 2020. doi:10.1093/infdis/jiaa397

Lee K, Ma W, Sikavi DR, et al. Cancer and Risk of COVID-19 Through a General Community Survey [published online ahead of print, 2020 Aug 26]. Oncologist. 2020;10.1634/theoncologist.2020-0572. https://pubmed.ncbi.nlm.nih.gov/32845538/

Kaneko, N., Kuo, H.-H., Boucau, J., Farmer, J.R., Allard-Chamard, H., Mahajan, V.S., Piechocka-Trocha, A., Lefteri, K., Osborn, M., Bals, J., Bartsch, Y.C., Bonheur, N., Caradonna, T.M., Chevalier, J., Chowdhury, F., Diefenbach, T.J., Einkauf, K., Fallon, J., Feldman, J., Finn, K.K., Garcia-Broncano, P., Hartana, C.A., Hauser, B.M., Jiang, C., Kaplonek, P., Karpell, M., Koscher, E.C., Lian, X., Liu, H., Liu, J., Ly, N.L., Michell, A.R., Rassadkina, Y., Seiger, K., Sessa, L., Shin, S., Singh, N., Sun, W., Sun, X., Ticheli, H.J., Waring, M.T., Zhu, A.L., Alter, G., Li, J.Z., Lingwood, D., Schmidt, A.G., Lichterfeld, M., Walker, B.D., Yu, X., Padera Jr., R.F., Pillai, S., and the Massachusetts Consortium on Pathogen Readiness Specimen Working Group, Loss of Bcl-6-expressing T follicular helper cells and germinal centers in COVID-19, Cell (2020), doi: https://doi.org/10.1016/ j.cell.2020.08.025.

Clinical Management and Outcomes Research

Bhimraj A, Morgan RL, Shumaker AH, et al. Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19 [published online ahead of print, 2020 Apr 27]. Clin Infect Dis. 2020;ciaa478. doi:10.1093/cid/ciaa478

Gandhi RT, Lynch JB, Del Rio C. Mild or Moderate Covid-19 [published online ahead of print, 2020 Apr 24]. N Engl J Med. 2020;10.1056/NEJMcp2009249. doi:10.1056/NEJMcp2009249

Gandhi RT. The Multidimensional Challenge of Treating COVID-19: Remdesivir is a Foot in the Door [published online ahead of print, 2020 Jul 31]. Clin Infect Dis. 2020;ciaa1132. doi:10.1093/cid/ciaa1132

Lang JP, Wang X, Moura FA, Siddiqi HK, Morrow DA, Bohula EA. A current review of COVID-19 for the cardiovascular specialist. Am Heart J. 2020;226:29-44. doi:10.1016/j.ahj.2020.04.025

Lee K, Ma W, Sikavi DR, et al. Cancer and Risk of COVID-19 Through a General Community Survey [published online ahead of print, 2020 Aug 26]. Oncologist. 2020;10.1634/theoncologist.2020-0572. https://pubmed.ncbi.nlm.nih.gov/32845538/

McCarthy CP, Murphy S, Jones-O'Connor M, et al. Early clinical and sociodemographic experience with patients hospitalized with COVID-19 at a large American healthcare system [published online ahead of print, 2020 Aug 19]. EClinicalMedicine. 2020;100504. doi:10.1016/j.eclinm.2020.100504

Meyerowitz EA, Kim AY, Ard KL, et al. Disproportionate burden of COVID-19 among racial minorities and those in congregate settings among a large cohort of people with HIV [published online ahead of print, 2020 Jun 25]. AIDS. 2020;10.1097/QAD.0000000000002607. doi:10.1097/QAD.0000000000002607

Siedner MJ, Gandhi RT, Kim AY. Desperate Times Call for Temperate Measures: Practicing Infectious Diseases During a Novel Pandemic. J Infect Dis. 2020;222(7):1084-1085. doi:10.1093/infdis/jiaa209

Siedner MJ, Gandhi RT. Proposing minimum requirements for announcing clinical trial results during the COVID-19 pandemic [published online ahead of print, 2020 Jul 8]. Clin Infect Dis. 2020;ciaa945. doi:10.1093/cid/ciaa945

Diagnostics

Vanuytsel K, Mithal A, Giadone RM, et al. Rapid Implementation of a SARS-CoV-2 Diagnostic Quantitative Real-Time PCR Test with Emergency Use Authorization at a Large Academic Safety Net Hospital [published online ahead of print, 2020 May 19]. Med (N Y). 2020;10.1016/j.medj.2020.05.001. doi:10.1016/j.medj.2020.05.001

Epidemiology

Chan AT, Brownstein JS. Putting the Public Back in Public Health - Surveying Symptoms of Covid-19 [published online ahead of print, 2020 Jun 5]. N Engl J Med. 2020;10.1056/NEJMp2016259. DOI: 10.1056/NEJMp2016259

Chan AT, Drew DA, Nguyen LH, et al. The COronavirus Pandemic Epidemiology (COPE) Consortium: A Call to Action. Cancer Epidemiol Biomarkers Prev. 2020;29(7):1283-1289. doi:10.1158/1055-9965.EPI-20-0606

Drew DA, Nguyen LH, Steves CJ, et al. Rapid implementation of mobile technology for real-time epidemiology of COVID-19. Science. 2020;368(6497):1362-1367. doi:10.1126/science.abc0473

Komorowski M, Kraemer MUG, Brownstein JS. Sharing patient-level real-time COVID-19 data. Lancet Digit Health. 2020;2(7):e345. doi:10.1016/S2589-7500(20)30132-1

Wu F, Zhang J, Xiao A, et al. SARS-CoV-2 Titers in Wastewater Are Higher than Expected from Clinically Confirmed Cases. mSystems. 2020;5(4):e00614-20. Published 2020 Jul 21. doi:10.1128/mSystems.00614-20

Pathogenesis

Atyeo C, Fischinger S, Zohar T, et al. Distinct Early Serological Signatures Track with SARS-CoV-2 Survival [published online ahead of print, 2020 Jul 30]. Immunity. 2020;S1074-7613(20)30327-7. doi:10.1016/j.immuni.2020.07.020

Bruchez A, Sha K, Johnson J, et al. MHC class II transactivator CIITA induces cell resistance to Ebola virus and SARS-like coronaviruses [published online ahead of print, 2020 Aug 27]. Science. 2020;eabb3753. doi:10.1126/science.abb3753

Chandrashekar A, Liu J, Martinot AJ, et al. SARS-CoV-2 infection protects against rechallenge in rhesus macaques [published online ahead of print, 2020 May 20]. Science. 2020;eabc4776. doi:10.1126/science.abc4776

Miller TE, Garcia Beltran WF, Bard AZ, et al. Clinical sensitivity and interpretation of PCR and serological COVID-19 diagnostics for patients presenting to the hospital [published online ahead of print, 2020 Aug 28]. FASEB J. 2020;10.1096/fj.202001700RR. doi:10.1096/fj.202001700RR

Shook LL, Shui JE, Boatin AA, et al. Rapid establishment of a COVID-19 perinatal biorepository: early lessons from the first 100 women enrolled. BMC Med Res Methodol. 2020;20(1):215. Published 2020 Aug 26. doi:10.1186/s12874-020-01102-y

Yonker LM, Neilan AM, Bartsch Y, et al. Pediatric SARS-CoV-2: Clinical Presentation, Infectivity, and Immune Responses [published online ahead of print, 2020 Aug 18]. J Pediatr. 2020;S0022-3476(20)31023-4. doi:10.1016/j.jpeds.2020.08.037

Therapeutics

Abraham J. Passive antibody therapy in COVID-19. Nat Rev Immunol. 2020;20(7):401-403. doi:10.1038/s41577-020-0365-7

Cai Y, Zhang J, Xiao T, et al. Distinct conformational states of SARS-CoV-2 spike protein [published online ahead of print, 2020 Jul 21]. Science. 2020;eabd4251. doi:10.1126/science.abd4251

Vaccines

Mercado NB, Zahn R, Wegmann F, et al. Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques [published online ahead of print, 2020 Jul 30]. Nature. 2020;10.1038/s41586-020-2607-z. doi:10.1038/s41586-020-2607-z

Yu J, Tostanoski LH, Peter L, et al. DNA vaccine protection against SARS-CoV-2 in rhesus macaques [published online ahead of print, 2020 May 20]. Science. 2020;eabc6284. doi:10.1126/science.abc6284

Zhao P, Praissman JL, Grant OC, et al. Virus-Receptor Interactions of Glycosylated SARS-CoV-2 Spike and Human ACE2 Receptor [published online ahead of print, 2020 Aug 24]. Cell Host Microbe. 2020;S1931-3128(20)30457-1. doi:10.1016/j.chom.2020.08.004

Zost SJ, Gilchuk P, Case JB, et al. Potently neutralizing and protective human antibodies against SARS-CoV-2. Nature. 2020;584(7821):443-449. doi:10.1038/s41586-020-2548-6